Application of Chromosomal Microarray Analysis in Oncology

Chromosomal microarray analysis (CMA) is a first-tier molecular cytogenetics test in the constitutional field helping to identify genetic causes of developmental delay, autistic spectrum disorders, or intellectual disability. CMA also plays a significant role in oncology where whole-genome sequencing or whole-exome sequencing are not yet offered as routine tests or when next-generation sequencing (NGS) panels and cytogenetics provide limited or inconclusive results.

In this webinar, Madina Sukhanova, assistant professor of pathology at Northwestern University Feinberg School of Medicine, will discuss the importance of CMA in oncology testing through a series of representative cases. These illustrative cases will demonstrate the utility of CMA combined with NGS assays to identify genetic aberrations associated with specific prognoses in different types of cancer.

Learning objectives:

• Learn how to investigate interesting oncology cases and findings.
• Gain a working knowledge of the importance of CMA and how it plays a vital role in oncology testing.
• Discover the utility of CMA combined with NGS.