Non-Coding RNA Analysis in Cancer: A Valuable Tool for Translational and Personalized Medicine

MicroRNAs are small, noncoding structures of about 19-25 nucleotides involved in the regulation of key cellular processes and cell communication. Their role in tumor tissue, the tumor microenvironment, and exosomes make them interesting candidates for therapeutic approaches in cancer.

MicroRNAs from both tissues and liquid biopsies are extensively studied as valuable biomarkers for early disease recognition, progression, and prognosis. MicroRNAs can also induce resistance or sensitization to specific cancer drugs. Evaluation of microRNAs using Agilent microarray technology will contribute to a better understanding of personalized cancer biogenesis, evolution, diagnosis, and treatment.

In this webinar, Dr. Cornelia Braicu and Dr. Ioana Berindan-Neagoe of Iuliu Hatieganu University of Medicine and Pharmacy will discuss:

• The pros, cons, and utility of different approaches that can support the exploitation of miRNAs as cancer biomarkers
• The utility of microarray technology for microRNA evaluation in personalized medicine
• Understanding and generating microRNA networks, plus examples of microRNA network analyses and discussion from therapeutic perspectives

 For Research Use Only. Not for use in diagnostic procedures.

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